Metal Allergies for a Total Knee Replacement, What Patients Need to Know: A Scoping Review

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Mark Bonardi

College:
The College of Health Professions and Human Services

Major:
Physical Therapy

Faculty Research Advisor(s):
Thomas Koc , Caitlin Boyko

Abstract:
Background: Total Knee Arthroplasty (TKA) revisions due to metal allergies are becoming more prevalent, resulting in increased cost and decreased patient outcomes. This study aimed to assess all factors involved in undergoing a TKA and TKA revision so that candidates may make the best possible decision.
Methods: Studies were identified through MEDLINE, Google Scholar, and CINHAL. Selection was based on level of evidence, publication date, and topics pertaining to TKA revision cost, revision outcomes, and metal allergy testing prior to TKA.
Results: TKA revisions led to increased recipient cost and a decrease in patient outcomes. No conclusive evidence was found that dermal patch testing or lymphocyte transformation test (LTT) can predict complications prior to a TKA.
Conclusion: Metal allergy screening should be done prior to undergoing a TKA to access possible risk and decrease potential costs. Potential recipients should be aware of costs, complications, and alternative treatments if metal allergies are found through testing.


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